Included in ACS Sensors Rising Stars in Sensing Special Issue
Zach's work developing rapid, on-the-spot sensors for cannabis was included in a special virtual issue on Rising Stars in Sensing, curated by Prof. Shana O. Kelley.
Yen & Christine defended their M.Sc. degrees
Congratulations to Yen Truong and Christine Wong for defending their M.Sc. degrees.
Canadian Cancer Society Research Institute Funding Received
Through the gracious support of the CCSRI, and in collaboration with Dr. Christine Addison, we have been awarded an Innovation Grant to evaluate aldehydes as imaging biomarkers of lung cancer prognosis using our radiotracer [18F]NA3BF3.
Funding for new PET/CT received
Thanks to generous funding from the Canadian Foundation for Innovation and the Province of Ontario, as well as support from the Vice-President Research Dr. Sylvain Charbonneau, we will be acquiring a new PET/CT to continue our radiotracer development program.
Ekidna Sensing, Inc., is launched!
Based off of our cannabinoid analysis technology, we have launched Ekidna Sensing, Inc., in order to commercialize our rapid, on-the-spot cannabinoid testing. More information can be found here.
On the cover of ACS Sensors
Zach's work developing rapid cannabinoid sensors was featured on the cover of ACS Sensors.
NSERC CGS-M & Michael Smith Supplement
Émile was awarded a Canada Graduate Scholarship (MSc) and a Michael Smith Supplement that will allow him to travel to work with Dr. Peter J.H. Scott at the University of Michigan. Great work Émile!
Technology for on-the-spot Cannabinoid analysis is patented!
In collaboration with Dr. Benoît Lessard and Dr. Cory Harris, we have filed a patent to protect our technology for rapid, low-cost, and accurate chemical analysis of cannabis plants and plant-derived products.
Our graduate students receive scholarships
Three of our graduate students, Nick Calvert, Yen Truong and Alexia Kirby, have just received the Ontario Graduate Student scholarship to support their studies. Congratulations Nick, Yen and Alexia!
Radiotracer for mapping aldehydic load in live subjects is published in Chem Comm
In this work we continue to build on the N-aminoanthranilic acid moiety for rapid, catalyst-free complexation of aldehydes in living systems, developing a radiotracer capable of mapping aldehydic load in living subjects using Positron Emission Tomography.
On the cover of ChemBioChem Probes & Sensors Special Issue
The cover illustrates our fluorogenic probes capable of speciation of biogenic aldehydes through fluorescent fingerprinting
On the inside front cover of Organic and Biomolecular Chemistry New Talent Special Issue
Here we apply our fluorogenic sensor for live cell imaging of aldehydic load following the induction of electrophilic stress. On the cover, labelled cells are raining down in front of a graffitied wall.
Our work on aldehyde fingerprinting on ChemistryViews
Recent work on the fluorogenic fingerprinting of biogenic aldehydes was reported in ChemistryViews. See the article here.
Imaging Aldehydic Load in live cells published in special issue
Expanding upon the capability of our fluorescent imaging of aldehydes, we have published work fully characterizing the reactivity of our aldehyde-conditional fluorogenic agent, as well as demonstrated its application to the imaging of Aldehydic Load via live cell microscopy. This work was an invited contribution to a New Talent issue of Organic & Biomolecular Chemistry.
Fluorescent fingerprinting of aldehydes published in special issue
Our collaborative effort with Dr. Rolland-Lagan on identifying biogenic aldehydes through curvature analysis of excitation-emission matrices was published as a Very Important Paper in a special issue on Probes in Chembiochem.
Our graduate students receive scholarships
Two of our graduate students, Yen Truong and Alexia Kirby, have just received the Ontario Graduate Student scholarship to support their studies. Congratulations Yen and Alexia!
Hosting Kelsee, Grace, and Tyra in our lab was a blast!
Thanks to support from the Verna J. Kirkness Foundation, Kelsee, Grace, and Tyra visited us from indigenous communities across Canada so we could give them a taste of the work we do in the Mol Med Lab. Listen to the story on CBC's Ottawa Morning here.
Aldehyde-conditional CEST-MRI contrast agent published
Our work developing a CEST-MRI contrast agent that selectively "turns on" when covalently bound to aldehydes was published in Chemistry: A European Journal.
We are CIHR funded!
A Project Scheme grant in collaboration with the Rayner (UOHI) and Pratt (uO Chemistry) groups entitled "Aldehydes, Antioxidants, and Atherosclerosis: Translational prognostic molecular imaging with novel prognostic and companion diagnostic agents" was supported by CIHR.
Industrial partnership established with Qu Biologics
Through an NSERC ENGAGE grant, we have initiated a collaboration with Qu Biologics to use PET/MRI to investigate the fate of their site-specific immunomodulators in mice.
Patent filed for our aldehyde sensing compounds
Our imaging and sensing probes for biogenic aldehyde detection was filed by uOttawa, opening up our technology for further development and industrial partnerships.
Our MRI has arrived!
An MR Solutions tunable field 3.0 T MRI obtained with CFI funding is now installed and ready to be used for pre-clinical contrast agent development.